US reviews first human loss of life associated to chicken flu

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Colored transmission electron micrograph of H5N1 virus particles

Science Photograph Library

An individual in Louisiana has died from a chicken flu virus often known as H5N1. That is the primary identified loss of life associated to the virus within the US. The Louisiana Division of Well being (LDH) has not recognized further H5N1 instances within the state nor discovered proof of person-to-person transmission, indicating that the danger to most people stays low.

The particular person was hospitalised for the virus in December, after contracting it from contaminated or useless birds of their yard. They skilled extreme respiratory signs. It was the primary severe case of H5N1 within the US. The LDH introduced their loss of life on 6 January and stated that they had been older than 65 and had underlying well being situations.

In complete, 66 individuals within the US have examined constructive for H5N1, based on the US Facilities for Illness Management and Prevention (CDC). Most of them developed delicate signs, equivalent to eye redness, and labored with contaminated cows or chickens.

H5N1, which has killed tens of hundreds of thousands of untamed and home birds worldwide, has been circulating in dairy cows throughout the US for nearly a 12 months now. Genetic evaluation of samples collected from the particular person in Louisiana point out that the particular person was contaminated with the D1.1 genotype of the virus, which has similarities to the viruses not too long ago detected in wild birds, however distinct from the model spreading in cattle. There isn’t any proof that the virus can transmit between individuals.

The evaluation additionally recognized a number of adjustments that will enhance the virus’ capability to bind to cells within the higher airways of people, which largely lack receptors for many chicken flu viruses. Based on the CDC, it’s possible these adjustments occurred after the particular person was contaminated – any time somebody contracts a chicken flu virus, it offers it an opportunity to evolve and turn out to be higher at spreading between us. One of many adjustments was additionally seen in an individual who fell severely ailing with H5N1 in Canada in November.

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